Lab Interests:
The Hoesli Stem Cell Bioprocessing Lab develops devices and cell culture methods for cellular therapy – in particular for islet transplantation. We have upscaled islet encapsulation processes using stirred or microchannel emulsification to produce large amounts (L volumes) of microencapsulated islets cells in less than an hour. Using 3D bioprinting, we are engineering 3D vascularized tissues to study islet interactions with endothelial cells and other vascular cells. These vascularized tissue constructs could one day be used for transplantation. Overall, we are using our knowledge of bioprocess engineering and materials engineering to service the islet biology and diabetes community.