University of Manitoba
My lab investigates how and why pancreatic Beta cells are destroyed in Type 1 Diabetes (T1D). We are interested in understanding how Beta cells respond to various forms of stress by adopting new fates and altering their functions. We also seek to understand how Beta cells communicate signals with other islet cells and infiltrating immune cells during the pathogenesis of T1D. We aim to discover molecular mechanisms that can be targeted to prevent Beta cell loss and dysfunction in T1D and other forms of diabetes.