Lab Interests:
We seek to improve life for people affected by diabetes by contributing to the development of new therapies, and ultimately a cure. The Kieffer lab has the capacity to address questions from molecular to cellular to whole organism. We have advanced equipment for high-throughput analyses of cellular function and pathways, for whole animal imaging, and for metabolic phenotyping. We utilize tissue-specific knockdown or reintroduction of genes, cell transplant and surgical manipulations, and human stem cells with targeted genetic engineering to model diabetes and generate insulin producing cells for automatic insulin replacement.